USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: P06753 USC-OGP 2-DE database:  P06753 P06753 General information about the entry View entry in simple text format Entry name TPM3_HUMAN Primary accession number P06753 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Tropomyosin alpha-3 chain; AltName: Full=Gamma-tropomyosin; AltName: Full=Tropomyosin-3; AltName: Full=Tropomyosin-5; Short=hTM5;. Gene name Name=TPM3 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1227: pI=4.66; Mw=34859 SPOT OGP-1237: pI=4.73; Mw=33231 SPOT OGP-1246: pI=5.01; Mw=31502 SPOT OGP-1248: pI=4.63; Mw=31413 Cross-references UniProtKB/Swiss-Prot P06753; TPM3_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TPM3_HUMAN Primary accession number P06753 Secondary accession number(s) D3DV71 P12324 Q2QD06 Q5VU58 Q5VU63 Q5VU66 Q5VU71 Q5VU72 Q8TCG3 Q969Q2 Q9NQH8 Sequence was last modified on  June 26, 2013 (version 2) Annotations were last modified on  March 15, 2017 (version 198) Name and origin of the protein Description RecName: Full=Tropomyosin alpha-3 chain; AltName: Full=Gamma-tropomyosin; AltName: Full=Tropomyosin-3; AltName: Full=Tropomyosin-5; Short=hTM5; Gene name Name=TPM3 Encoded on Name=TPM3 Keywords Acetylation; Actin-binding; Alternative splicing; Chromosomal rearrangement; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disease mutation; Isopeptide bond; Muscle protein; Nemaline myopathy; Phosphoprotein; Proto-oncogene; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X04201; CAA27798.1; -; mRNA EMBL AY004867; AAF87083.1; -; mRNA EMBL X04588; CAB37185.1; -; mRNA EMBL AL590431; CAH71264.1; -; Genomic_DNA EMBL AL590431; CAH71269.1; -; Genomic_DNA EMBL CH471121; EAW53229.1; -; Genomic_DNA EMBL CH471121; EAW53230.1; -; Genomic_DNA EMBL CH471121; EAW53231.1; -; Genomic_DNA EMBL CH471121; EAW53235.1; -; Genomic_DNA EMBL BC000771; AAH00771.1; -; mRNA EMBL BC008407; AAH08407.1; -; mRNA EMBL BC008425; AAH08425.1; -; mRNA EMBL BC015403; AAH15403.1; -; mRNA EMBL BC072428; AAH72428.1; -; mRNA EMBL DQ120714; ABC40673.1; -; Genomic_DNA EMBL X03541; CAA27243.1; ALT_TERM; mRNA EMBL AF474157; AAL84570.1; -; mRNA CCDS CCDS1060.1; -. [P06753-2]; . CCDS CCDS41400.1; -. [P06753-5]; . CCDS CCDS41401.1; -. [P06753-4]; . CCDS CCDS41402.1; -. [P06753-3]; . CCDS CCDS41403.1; -. [P06753-1]; . CCDS CCDS60274.1; -. [P06753-7]; . CCDS CCDS60275.1; -. [P06753-6]; . PIR A25530; A25530; . PIR S06210; A24199; . RefSeq NP_001036816.1; NM_001043351.1. [P06753-5]; . RefSeq NP_001036817.1; NM_001043352.1. [P06753-3]; . RefSeq NP_001036818.1; NM_001043353.1. [P06753-4]; . RefSeq NP_001265118.1; NM_001278189.1. [P06753-6]; . RefSeq NP_001265120.1; NM_001278191.1. [P06753-7]; . RefSeq NP_689476.2; NM_152263.3. [P06753-1]; . RefSeq NP_705935.1; NM_153649.3. [P06753-2]; . UniGene Hs.535581; -; . UniGene Hs.578978; -; . UniGene Hs.644306; -; . UniGene Hs.654421; -; . ProteinModelPortal P06753; -; . SMR P06753; -; . BioGrid 113023; 128; . IntAct P06753; 60; . MINT MINT-1142638; -; . STRING 9606.ENSP00000357516; -; . iPTMnet P06753; -; . PhosphoSitePlus P06753; -; . SwissPalm P06753; -; . DMDM 519668659; -; . DOSAC-COBS-2DPAGE P06753; -; . SWISS-2DPAGE P06753; -; . EPD P06753; -; . MaxQB P06753; -; . PaxDb P06753; -; . PeptideAtlas P06753; -; . PRIDE P06753; -; . Ensembl ENST00000302206; ENSP00000307712; ENSG00000143549. [P06753-7]; . Ensembl ENST00000323144; ENSP00000357518; ENSG00000143549. [P06753-4]; . Ensembl ENST00000328159; ENSP00000357520; ENSG00000143549. [P06753-6]; . Ensembl ENST00000330188; ENSP00000339035; ENSG00000143549. [P06753-5]; . Ensembl ENST00000368530; ENSP00000357516; ENSG00000143549. [P06753-1]; . Ensembl ENST00000368531; ENSP00000357517; ENSG00000143549. [P06753-3]; . Ensembl ENST00000368533; ENSP00000357521; ENSG00000143549. [P06753-2]; . GeneID 7170; -; . KEGG hsa:7170; -; . UCSC uc001fdy.2; human. [P06753-1]; . CTD 7170; -; . DisGeNET 7170; -; . GeneCards TPM3; -; . GeneReviews TPM3; -; . HGNC HGNC:12012; TPM3; . HPA HPA000261; -; . HPA HPA009066; -; . HPA HPA047089; -; . HPA HPA053624; -; . MalaCards TPM3; -; . MIM 164970; gene; . MIM 191030; gene; . MIM 255310; phenotype; . MIM 609284; phenotype; . neXtProt NX_P06753; -; . OpenTargets ENSG00000143549; -; . Orphanet 171881; Cap myopathy; . Orphanet 171439; Childhood-onset nemaline myopathy; . Orphanet 2020; Congenital fiber-type disproportion myopathy; . Orphanet 178342; Inflammatory myofibroblastic tumor; . Orphanet 171433; Intermediate nemaline myopathy; . PharmGKB PA36692; -; . eggNOG KOG1003; Eukaryota; . eggNOG ENOG410XR5K; LUCA; . GeneTree ENSGT00550000074494; -; . HOGENOM HOG000231522; -; . HOVERGEN HBG107404; -; . InParanoid P06753; -; . KO K09290; -; . OMA XKCSELE; -; . OrthoDB EOG091G0UO7; -; . PhylomeDB P06753; -; . TreeFam TF351519; -; . Reactome R-HSA-390522; Striated Muscle Contraction; . Reactome R-HSA-445355; Smooth Muscle Contraction; . ChiTaRS TPM3; human; . GeneWiki Tropomyosin_3; -; . GenomeRNAi 7170; -; . PRO PR:P06753; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000143549; -; . CleanEx HS_TPM3; -; . ExpressionAtlas P06753; baseline and differential; . Genevisible P06753; HS; . GO GO:0015629; C:actin cytoskeleton; IDA:HPA; . GO GO:0005884; C:actin filament; IBA:GO_Central; . GO GO:0005856; C:cytoskeleton; NAS:UniProtKB; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005862; C:muscle thin filament tropomyosin; TAS:UniProtKB; . GO GO:0001725; C:stress fiber; IDA:MGI; . GO GO:0051015; F:actin filament binding; IBA:GO_Central; . GO GO:0008307; F:structural constituent of muscle; IBA:GO_Central; . GO GO:0007015; P:actin filament organization; IBA:GO_Central; . GO GO:0006928; P:movement of cell or subcellular component; TAS:UniProtKB; . GO GO:0006936; P:muscle contraction; IBA:GO_Central; . GO GO:0030049; P:muscle filament sliding; TAS:Reactome; . InterPro IPR000533; Tropomyosin; . Pfam PF00261; Tropomyosin; 1; . PRINTS PR00194; TROPOMYOSIN; . PROSITE PS00326; TROPOMYOSIN; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]